MOTU Virtual Instruments and Big Sur or Later
MachFive, Ethno Instrument, BPM, Electric Keys, and Symphonic Instrument (any version) are not compatible with macOS Big Sur or later.
As a workaround, the UVI Workstation instrument (free) can read the soundbank libraries from all of these products and can be installed on macOS Big Sur.
Visit the link below to download and install UVI Workstation:
https://www.uvi.net/uvi-workstation.html
After it's installed, move the soundbanks for MachFive, Ethno Instrument, BPM, Electric Keys or Symphonic Instrument to the following location on your computer:
Mac: Macintosh HD/Library/Application Support/UVISoundBanks
Win: C:/ProgramFiles/UVISoundBanks
IMPORTANT: Be sure to download the latest updated soundbank (UFS) files from motu.com/download.